ITGA4 anticorps

N° du produit ABIN7595333

Cet anticorps Souris Monoclonal détecte spécifiquement ITGA4 dans IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour ITGA4 anticorps (ABIN7595333)

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA4 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: OSX14

Détail du produit anti-ITGA4 anticorps

Fonction: Mouse monoclonal to Integrin alpha 4: OSX14 clone

Specificité: Specific for Integrin α,4

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: Integrin alpha 4

Isotype: IgG

Information d'application

Indications d'application: IHC. A dilution of 1 : 500 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur ITGA4

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Autre désignation: Integrin alpha 4

Sujet: FUNCTION: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.

Pathways: Integrin Complex